SBPA · STRUCTURE / PROPERTY / BIOACTIVITY

Design the structure. Predict the function.

Our goal: predict how particle structure and surface chemistry shape biological response. Compare candidate designs, understand uncertainty and choose which particles to make and test.

01

Evidence

Cryo-EM, cryo-ET, SAXS and published S-layer assembly data define the supported structural space.

02

Surrogate

Fast models relate interface descriptors to assembly, permeability, corona formation and uptake.

03

Oracle

Uncertainty and expected information gain determine which structure, concentration or assay should be tested next.

04

Decision

A traceable design shortlist keeps evidence, prediction, limits and the next verification step together.